|
Showing 1 - 9 of
9 matches in All Departments
This book presents and describes the various uses of gastric bypass
in bariatric and metabolic surgery and outlines the different
techniques currently available. Furthermore, the possible
complications with the procedure and ways to avoid them are also
discussed. The use of the gastric bypass for the treatment of
diabetes is emphasized and the new indications for the operative
treatment of diabetes are featured in detail. Endoscopic uses
concerning the gastric bypass are also addressed, covering
preoperative evaluation, complications treatment, weight regain
treatment and endoscopic treatment of obesity. The most advanced
techniques and new technologies available for performing gastric
bypass surgeries are presented in the most didactic possible way,
making use of value-added learning features throughout the
text.Gastric Bypass - Bariatric and Metabolic Surgery Perspectives
is intended as a practical guide for all those interested and
involved with bariatric surgery, including general surgeons,
bariatric surgeons, GI surgeons and surgery residents.
Primary microcephaly (MCPH) is neurological disorder. It exhibits
genetic heterogeneity. The genes identified in MCPH are
Microcephalin gene at MCPH1 locus, WDR62 at MCPH2, CDK5RAP2 gene at
MCPH3 locus, CEP152 at MCPH4, ASPM at MCPH5 locus, CENPJ at MCPH6
locus and STIL/SIL at MCPH7 locus. The objective of this study was
to identify families from Punjab and to perform homozygosity
mapping and DNA sequencing for mutation detection. We reported
c.3978G>A; p.W1326X mutation in ASPM gene of MCPH families from
Punjab. This is the most prevalent gene investigated for mutations
in Pakistan. The identification of common mutation in ASPM gene in
families with primary microcephaly analyzed in this study from
Punjab and several other families of an apparently different ethnic
group (Pashtun) revealed most probable involvement of common
ancestry for this variant in these MCPH families. Further data
should be explored so that centres for genetic counseling could be
established to guide the people for avoiding blood relation
marraiges.
Acute lymphoblastic leukemia (ALL) is a malignant disease caused by
the abnormal growth and development of early non-granular white
blood cells, or lymphoblasts. ALL occurs predominantly in children,
peaking at 4 years of age. Interferons (IFNs) are the biological
agents involved in the antiviral responses and the inhibition of
tumor growth. In oncology, the IFNs are an important treatment
options for a number of solid tumors and hematological
malignancies. The IFN- 1gene consists of 840 bp and it lacks intron
sequences. Seventy patients suffering from Childhood Acute
Lymphoblastic Leukemia were studied and analyzed for mutation
analysis of IFN- 1. So, 58.3% of the patients suffering from ALL
were observed and compared with 41.7% normal DNA samples as
control. PCR was performed and amplified gene products were
detected on agarose gel and PAGE. Finally, SSCP was performed and
mobility shift was observed in 7 out of 70 ALL samples. We observed
that ALL disease typically develops in children ages 1-10 years old
and is more prevalent in males than females. Mutation in the IFN- 1
gene was significantly related to 1-5 years in case of association
of mutation with age.
Risks of nuclear terrorism and blackmailing have increased
significantly in recent years mainly because of three factors: the
growth and spread of nuclear weapons, the expansion of civilian
nuclear programs and the increase in extremist religious and
political groups waging campaigns of terror. The growing danger
encompasses much of the world. Lax or inadequate security over
nuclear materials and weapons in one country could be exploited to
trigger atomic blackmail and terrorism elsewhere. Inadequate
security at nuclear facilities also could provide extremists waging
a campaign of terror within a nation, an opportunity to create a
situation of national terror by seizing or sabotaging a civilian
nuclear power plant or a research reactor or a laboratory. These
threats are alarming and should be calculated as credible sources
of emerging trends in terrorism. The general field of interest
within which this study is located is nuclear terrorism with a
particular focus on possible scenarios such as the theft of fissile
material, dirty bombs etc. The main geographical area to be focused
on is Pakistan although the study will also refer to terrorist
organizations pursuing WMDs.
Cancer is an un-control growth of cells. Cancer cells grow in an
abnormal fashion, crowd out the normal cells. Liver is the largest
organ inside the body; hepatocellular carcinoma is a cancer arising
from liver. Laryngeal cancer affects the larynx, which is often
called voice box, common in males. Lung cancer is the deadliest
cancer in the world, leading cause of death from cancer in men.
Multiple gene mutations are involved in cancer pathology. Type I
interferons (IFN, IFN, IFN ) are the proteins involved in cell
signaling and growth. This study was conducted to determine whether
mutation in IFN 1 plays a significant role in liver, larynx and
lung cancer. Paraffin embedded tissues of liver, larynx and lung
were used for DNA isolation. SSCP technique was used to detect
mutation. Only two samples of lung carcinoma shows the mobility
shift on SSCP gel. It was observed that people in older age have
more chances of cancer. In general population, males are more prone
to larynx and lung cancer than female. Significant values were
observed (p
Ontology development is a systematic technique to represent the
existing and new knowledge about a specific domain by using some
models to present the system in which conceptualization is
involved. This book presents the use of ontology to formally
represent ontology-based competence model for potential users of
quality registry report in a health care organization. The model
describes the professional and occupational interests and needs of
the users through structuring and describing their skills and
qualifications. There are two main parts of our competence model:
general competence and occupational competence. The model is
implemented in protegee 4.0. Although our competence model gives
the general view about all medical areas in a hospital, from
implementation point of view, we have considered only Cardiology
area in detail. A user can get information about the patient and
specific disease with treatment tips by using various
organizational resources: i.e. quality registries, medical reports
and online journals. Our model also provides a support of
information filtering which filters the information according to
the need and the competencies of the users.
Das Fasten im Monat Ramadan ist eine der funf "Saulen" des
islamischen Glaubens. Es bedarf keiner Beweisfuhrung, dass das
Fasten eine islamische Pflicht ist und dass aus der islamischen
Gemeinschaft austritt, wer dies leugnet, denn es ist so offenkundig
wie das Gebet. Und in Anbetracht einer Sache, die so eindeutig klar
ist, haben Gelehrte und Ungebildete, Alte und Junge die gleiche
Haltung.........
|
|